Peyronie’s Disease involves often painful curvature of the penis resulting in scar tissue or plaque formation. This can be due to repeated trauma to the penis from sex or activity, however, we still do not know all possible causes of the condition. For many, the visual and aesthetic concern of the penis is more significant than the medical concern. In other words, many men are concerned about how the penis looks rather than its function.
However, many men will see a worsening in their Peyronie’s disease, which may eventually interfere with or disallow sex. If conservative treatments and time have not improved Peyronie’s, we may consider further intervention. Some men will opt for medical management of the disease. While these drugs are not necessarily incredibly effective, they may reassure the patient and allow them to accept some minor curvature as normal and a new part of their lives. Injection therapy is often the next, most appropriate step. Currently, there is one injection used for Peyronie’s that has solid data supporting its use. Xiaflex is injected directly into the scar tissue to soften the plaque and improve both curvature and discomfort.
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