Author: Akash Kapadia, MD

Are Viagra (Sildenafil) and Cialis (Tadalafil) Interchangeable?

Man popping blue pills out of packaging next to glass of water

With all the novel medical and surgical therapies developed over the past few decades to address Erectile Dysfunction or ED, two remain stalwarts in the front-line fight to improve erectile function. These, of course, are Viagra and Cialis, generically known as Sildenafil and Tadalafil, respectively. Both drugs are PDE 5 inhibitors, which essentially relax the muscles in the lining of the arteries, allowing them to expand and delivering more blood as a result. Being that ED is a primarily vascular concern, this increased blood flow is exceptionally important for continued erectile function and sexual health.

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Comparing Viagra/Sildenafil to Cialis/Tadalafil

When patients find that they need erectile dysfunction/ED medication, their mind often goes straight to which medication is best. This decision can be challenging with all of the marketing swirling around ED treatment. Ultimately, however, the two most commonly known medications on the market are Sildenafil, the generic version of Viagra, and Tadalafil, the generic version of Cialis. Other than the dosages – 100 mg maximum for sildenafil and 20 mg maximum for Tadalafil, the two drugs have similarities and differences that every patient should know and understand.

For one, both are PDE5 inhibitors, which relax and widen blood vessels to allow for increased blood flow. This is the primary mechanism of their effectiveness, and it’s why they are so good for mild to moderate ED.

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Choosing Between In-Office and Surgical BPH Treatment

Benign prostatic hyperplasia, or BPH, is a common concern as men age and represents a significant cause of lower urinary tract symptoms ranging from mild to severe. Due to the prevalence of this condition, there are plenty of treatment options, from medication to office therapies and surgery. With all the available options, it can be confusing for patients to make the best choice for their circumstances. This article will discuss office versus surgical treatment options and when they make the most sense for your circumstances.

When patients first begin to experience lower urinary tract symptoms, many believe that they may have prostate cancer. However, prostate cancer rarely presents with urinary symptoms in its earlier stages. Most patients are relieved to find out that their symptoms are caused by benign prostatic enlargement, and they often, at this point, may or may not pursue therapy. Unfortunately, BPH is a progressive condition and tends to get worse. The gradual worsening, however, is often managed through lifestyle changes, including not going out to events or dinner or limiting fluid intake. These slowly creep up on a man, and their life can be severely limited before they know it. Many patients do not understand the breadth of minimally invasive options, including in-office ones, and consequently wait too long for treatment.

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Bent Penis? How Peyronie’s Disease Affects Your Physical and Mental Health

Man in distress putting hands over face

Peyronie’s Disease, or PD, is an abnormal deformity of the penis that often presents as a bend or curve of the penis, but it may also present as narrowing, indentation, flopping, or ‘hourglassing’ of the penis. Peyronie’s disease or PD is common and affects up to 10% of men over the age of 40. It is often caused by micro-trauma or ‘wear and tear’ of the penis, but it can also be genetic. While not every bent penis needs treatment, it is important to recognize the physical and psychological impact of PD and learn whether your condition needs treatment. Determining whether treatment is needed can often be as much of a psychological question as a physical one. Why? Not all cases of Peyronie’s are painful, and not all instances inhibit a regular and enjoyable sex life.

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Eroxon Topical Erectile Gel

Man squeezing gel out of tube into hand

You may have heard of a new erectile dysfunction therapy known as Eroxon (MED 3000) that the FDA recently approved for over-the-counter use. It is a topical gel marketed in Europe and the UK as a faster way to gain an erection versus Viagra or Cialis, and their generic forms sildenafil and tadalafil, respectively. However, while this sounds like a fantastic erectile dysfunction therapy, does it work?

Before determining whether this particular gel works, we should discuss the history of topical erectile dysfunction gels and formulations. This very short discussion centers around the fact that we have tried to create topical versions of several medical therapies, including, for example, trimix, which is otherwise used as an injection into the penis, without any success – the simple fact is that, to date, we do not have a reliable therapy that functions topically.

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P-Shots for Erectile Health. Legit?

Doctor with gloves filling injection

You may have heard of the term biohacking. It’s a colloquialism now used for a practice that is centuries, if not millennia, old – fine-tuning the body to extract the highest and best performance. A favorite therapy of Biohackers is known as platelet-rich plasma therapy, posited as a rejuvenation therapy, and is used in several applications. Orthopedic surgeons use it to help rejuvenate joints. Hair loss specialists claim it may assist with regrowth, especially in those with androgenic alopecia or male pattern baldness. Plastic surgeons use it for facial skin rejuvenation – the list goes on.
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The Stages of Incontinence After Prostatectomy

Older man walking along nature path

Before we get into the details about incontinence after prostatectomy, we must discuss Prostate Specific Antigen (PSA) and how we have modified our diagnostic process and, ultimately, treatment of prostate cancer over the years. You may have read elsewhere on our website that we once used to aggressively treat prostate cancer at the first signs of PSA rising above 4. As we have learned over the years, prostate cancer is often very slow-growing, and a single high PSA reading does not necessarily warrant a biopsy or treatment. Similarly, the presence of prostate cancer with a biopsy does not necessarily mean an immediate prostatectomy. The restraint we have shown with this newer knowledge of prostate cancer has reduced the number of prostatectomies we’ve had to perform and ultimately helped some patients avoid the consequences of such surgery, including incontinence and erectile dysfunction.

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Does Cranberry Juice Work for Kidney Stones?

person pouring cranberry juice into glass

It may seem too simplistic and even ridiculous, but we’ve all been told that cranberries and their juice effectively prevent kidney stones. However, before you go out and drink liters of cranberry juice at a time, we must discuss some other ways to mitigate kidney stones and what you should do if you develop them.

Kidney stones are hardened crystals that develop within the kidneys for several potential reasons. Kidney stones do not cause pain for many as they are small enough to pass through the urinary system without us ever knowing. For some, however, kidney stones can develop to be quite large. While the stones remain in the kidneys themselves, they are usually asymptomatic. However, if they begin to migrate into the ureters – the tubes that carry urine from the kidneys to the bladder – they can cause significant pain and other complications. For some, kidney stones represent a harrowing circumstance, which may require passing the stone over a day or two or intervention from a urologist using shockwave therapy or lithotripsy. However, it’s important to remember that if you develop a fever or other signs of infection, this is an emergency that must be treated at the hospital. Kidney infections progress very rapidly and can be devastating if not treated early.

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Will My ED Treatment Cause Priapism?

woman handing man meds in bed

When discussing erectile dysfunction, or ED, most men are laser-focused on treatments to eliminate the embarrassment and lack of function. Because erectile function plays a significant psychological and physical role in our lives and lifestyles, we are often predisposed to trying almost everything to eliminate it, sometimes with little regard for the consequences. From supplements to pills and injections to implants, there is no lack of options when choosing how to treat ED.

Of course, each of the erectile dysfunction treatment options on the market today has side effects. Fortunately, due to the number of studies and funding put into these treatments, most options are relatively safe with minor side effects. However, a significant issue, considered an emergency, can arise from specific erectile dysfunction treatments. That concern, albeit rare, is priapism – an erection lasting more than four hours.

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TESE, Micro-TESE, and Low Testosterone

Woman on husbands back with arms around chest, both smiling

TESEs were first performed in the early 1990s and provided men with a fertility option even if semen analysis showed no sperm – known as azoospermia. This ushered in an era of male fertility options that allowed urologists to retrieve sperm in about 30% of men, ultimately resulting in about 25% of men being able to become fathers. With 1% or so of all American men not having usable sperm in their semen, this was a major step forward.

Around the same time, we began to understand the landscape of male versus female infertility, and we now know that about a third of all infertility issues can be attributed to the male patient, a third to the female patient, and a third to both. So, finding a way to improve male fertility has addressed a key concern of couples struggling to conceive.

The TESE and even micro-TESE is an invasive procedure used for sperm extraction from the testes. Both require cutting into the testicle, at which point the urologic surgeon tests areas of the testicle for sperm. If sperm are found, they are extracted for later insemination.

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